30 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Abnormal Coagulation Tests ... Abnormal #APTT #Laboratory ... #Hematology #Diagnosis ... #Workup
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Study • Clotting tests ... • Clotting tests ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
ACTH stimulation test ... confirmation of autoimmune-mediated ... Insufficiency #Evaluation #laboratory ... #diagnosis #testing ... endocrinology #workup
Bayesian combination of 4T score with Heparin PF4 antibody titer to obtain the post-test probability of
obtain the post-test ... PF4Antibody #Bayesian #Diagnosis ... #Hematology #HITT ... Thrombocytopenia #Laboratory
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
DAT Results in Autoimmune ... #antiglobulin #test ... #DAT #Autoimmune ... #Hemolysis #hematology ... #diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Membrane): - Autoimmune ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... antibody (ANA) test ... ; if positive, test ... Screening Tests ... #workup #diagnosis
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Vascular imaging → Test ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
• Underfilled test ... Thromboplastin #laboratory ... #hematology #diagnosis
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... Presence of atypical laboratory ... tests (e.g., AST ... #Hepatology #AIH