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hematology causes algorithm hemolytic classification extravascular oncology agglutinin aids atlas cold deficiency dermatology disease disorders ferritin fever hiv hodgkins iron
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... Diagnosis Algorithm ... circulation - Infections ... anemia • ... Differential #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Diagnosis Secondary ... ): • Acute infection ... malignancies • Anemia ... iron deficiency, hemolysis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Myelofibrosis Infectious ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential ... • Iron loss: Intravascular ... ) hemolysis, Intensive ... athletic training, Pulmonary
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
PD deficiency, Pulmonary ... Thrombotic idiopathic thrombocytopenia ... , Disseminated intravascular ... Morphology #Atlas #key #diagnosis ... #differential #
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Schistocytes, thrombocytopenia ... inclusions - If infection ... #Anemia #Differential ... #workup #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... drug induced • Infections ... IVIG infusion Intravascular ... #Anemia #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... reflection of intravascular ... anemia Indirect ... WBC count and differential ... #Workup #Hematology
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