29 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... ) vs Indirect (Hemolytic ... Transaminase >> Alkaline ... #FunctionTest #LFTs ... Transaminitis #diagnosis #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... : - Enzymes that ... Highest • Bone • Liver ... Intestine - Other causes ... Diagnosis #Algorithm #hepatology
Causes of Hemolytic Anemia - Differential Diagnosis
Inherited
 • Membrane
 • Internal
    - Hemoglobin
Causes of Hemolytic ... Anemia - Differential ... Hemoglobin - Enzyme ... #Anemia #Differential ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... microangiopathy: Thrombotic thrombocytopenic ... Intrinsic RBC Defects: Enzyme ... #differential # ... diagnosis #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... of Pregnancy (AFLP ... defects. 1) HELLP (Hemolysis ... child * Severe cases ... #obstetrics #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential ... elliptocytosis - RBC Enzyme ... anemia • ... #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
for Hemolytic Anemia ... : • Enzyme deficiencies ... : • Liver disease ... #Anemia #Differential ... classification #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
enzymes, and Low ... , Thrombocytopenia ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential