47 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... practices that could cause ... decreased PLT count: CBC ... patients if the cause ... of thrombocytopenia
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... following EtOH induced thrombocytopenia ... Diagnosis #Algorithm #Causes
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... is rare (< 10% cases ... ), cough (30% cases ... • Anemia and thrombocytopenia
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
immune thrombotic thrombocytopenia ... platelet count (thrombocytopenia ... The exact cause ... antibodies which cause ... #COVID #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
transfusion • Thrombocytopenia ... protein C and S Pathophysiology ... coagulopathy - Thrombocytopenia ... Treat primary cause ... Coagulation #diagnosis #causes
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- BMP, cap, CBC ... rhabdo/TLS) Causes ... AcuteKidneyInjury #AKI #Nephrology ... Diagnosis #Algorithm #Causes
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
an identifiable cause ... The cause is unknown ... #Bells #Palsy #neurology ... #anatomy #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Systemic effect -> Nausea ... alopecia (unusual), thrombocytopenia ... #SideEffects #Pathophysiology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAIDs cause vasoconstriction ... use shouldn't cause ... ACEIARB #Effects #Nephrology ... #Renal #Pathophysiology
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
be the primary cause ... - Cytokines #Pathophysiology ... #Nephrology #CKD