11 results
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... Coagulation Tests PT ... EricsMedicalLectures/ #Anticoagulants ... #Tests #Anticoagulation ... #Testing #Diagnosis
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... Patient Receiving Anticoagulants ... Prolonging the PT ... APTT #prolonged #diagnosis ... #hematology #evaluation
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid ... aPL): • Lupus anticoagulant ... patients to be diagnosed ... Guidelines): • Anticoagulation ... #management #anticoagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor and lupus anticoagulant ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... deficiency • Anticoagulant ... #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
heparin - Other anticoagulants ... inhibitors e.g. antiphospholipid ... inhibitor e.g. antiphospholipid ... Prolonged #Causes #diagnosis ... #differential #hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... antibodies) • Antiphospholipid ... (ß2GP), Lupus Anticoagulant ... Autoantibodies #Rheumatology ... #diagnosis #associations
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #clot #PT ... #PTT #diagnosis ... #models #hematology ... pathophysiology #anticoagulation ... #anticoagulant
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
pericarditis • Hematologic ... Immunologic domains: • Antiphospholipid ... units or lupus anticoagulant ... Erythematosus #diagnosis ... #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... nuclear antigen - Antiphospholipid ... test for lupus anticoagulant ... hemolytic anemia #Diagnosis ... #Rheumatology #
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis ... treatment #management #hematology