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differential causes anemia management oncology hemolysis hemolytic hepatology leukemia product vasculitis basophilia basophils cancer chronic clinical clinicopathology cll cryofibrinogenemia cutaneous
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... TPO, TPO-RA • Infections ... : Chronic infections ... bacterial and viral infections ... #Algorithm #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... the total white blood ... Diabetes/DKA Infections ... : • helminth infections ... #causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... syndrome - Thrombotic ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... #hematology #anemia
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... allergy, drug reaction ... , infection, neoplasms ... Strongyloides infection ... #hematology #eosinophilia
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... drug induced • Infections ... • Transfusion reactions ... #causes #classification ... #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... AIHA, Transfusion reactions ... Internal (RBC) - Infections ... - Peripheral Blood ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Algorithm Low ... Inflammation, Chronic Infection ... #Anemia #MCV #Classification ... #Hematology
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
- Differential Diagnosis ... Algorithm Transudate ... Superior vena cava ... Urinothorax Exudate - Infectious ... #Algorithm #Hepatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
(AHTR): Occurs during ... Infection - Infection ... likely to cause infections ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
• Infection - ... Infection occurs ... likely to cause infections ... #Transfusions #diagnosis ... #management #hematology
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