53 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
triad: Fever, Arthralgia ... /arthritis, Skin ... rash ± odynophagia ... #Disease #diagnosis ... management #treatment #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Rash • Human ... • Rheumatic fever ... gangrenosum • IBD ... differential #diagnosis ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... maculopapular rash ... #Disease #AOSD ... #rheumatology #diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... maculopapular skin ... #Adult #onset #Stills ... #diagnosis #rheumatology
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... criteria: - Fever ... weeks - Typical skin ... #Criteria #Diagnosis ... #Major #Minor #Rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Insect stings Disease ... symptoms - Headache, fever ... Nausea, abdominal pain ... Cold #Urticaria #diagnosis ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... infection • Still's ... Scleroderma Thickened skin ... #differential #diagnosis ... #rheumatology
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Purpura Fulminans Skin ... Exam 60 year old ... splenectomy 1d chills ... BIDMC Infectious Diseases ... #photo
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework ... Legg-Calve-Perthes disease ... • Bursitis • IBD ... - HIV - Lyme disease ... /swelling - Fever
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Sjögrens (15%) Skin ... lesions Abdominal pain ... (20%) Renal disease ... #rheumatology