23 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD ... lesions • Discoid lupus ... #differential #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
patients < 50 yrs old ... ; F>M Signs/Symptoms ... skin lesions ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin ... Malar (butterfly) Rash ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Schonlein Purpura (HSP ... , IgA Vasculitis ... ) 55 year old ... #clinical #photo ... #dermatology #skin
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Moccasin-variety Tinea ... Over the years: rash ... Diagnosis? ... skin of inflamed ... type #clinical #photo
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Schonlein Leg Rash ... 45 years old, seen ... later confirmed by skin ... #clinical #photo ... #dermatology #HSP
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin ... Rash - Differential ... Auspitz sign, Koebner's ... Herald's atch • Tinea ... soles • Discoid Lupus
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... and Symptoms: ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus