43 results
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
- Differential Diagnosis ... of hair, eyes, skin ... sclerosis (white "ash ... • Addison's disease ... McCune Albright syndrome
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... block • Sjogren syndrome ... Treatment: • Mild ... #SLE #Summary #diagnosis ... #rheumatology #management
Central Distribution, Febrile / Ill:
 - Viral Exanthem 
 - Lyme Disease (erythema migrans) 
Central Distribution,
Exanthem - Lyme Disease ... Stevens-Johnson Syndrome ... Macules #Papules #Rash ... #Algorithm #Diagnosis ... #Dermatology #Skin
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... #differential #diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... Differential Diaqnoses ... solid cancers • Systemic ... #diagnosis #management
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
and Associated Syndromes ... fashion- onion skin ... Pathogenesis "IL6 ... syndrome" Plasma ... #Variants #Diagnosis
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... like “butterfly rash ... #Differential #Diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... sudden onset of a rash ... - Rash: multiple ... general feeling of ill ... #diagnosis #dermatology
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Purpura Fulminans Skin ... Exam 60 year old ... shock, multiorgan system ... BIDMC Infectious Diseases ... #photo
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... rash in association ... withdrawal • Mild ... SinaiBmoreIMRes #DRESS #Syndrome ... #management