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bruising algorithm arterial venous anemia aptt atlas clots embolism hemolysis hemolytic hemorrhage hemostasis key management morphology obgyn obstetrics pathophysiology pediatrics
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
vs Extravascular ... Causes Intravascular ... intravascular coagulation ... #Causes #differential ... #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Thrombocytopenia ... Destruction • Abnormal ... Intravascular Coagulation ... #Causes #Hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... - Differential ... endocarditis) - Disseminated ... intravascular coagulation ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... #DIC #Disseminated ... #Intravascular ... #Coagulation #diagnosis ... #management #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
succenturiate lobe • Abnormal ... purpura (ITP) • Thrombotic ... HELLP syndrome • Disseminated ... intravascular coagulation ... (DIC) • Anti-coagulation
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Liver diseases, Bleeding ... (ITP), Disseminated ... intravascular coagulopathy ... #differential # ... hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
syndrome - Thrombotic ... purpura - DIC ... (disseminated intravascular ... coagulation) ... #differential #
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential ... Heparin-induced thrombocytopenia ... - Disseminated ... intravascular coagulation ... pathophysiology #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Disseminated intravascular ... coagulation (DIC ... #diagnosis #differential ... #hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
associated with thrombosis ... liver failure, disseminated ... intravascular coagulation ... discern these causes ... #Diagnosis #Hematology
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