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diagnosis erythematosus differential systemic treatment antinuclear signs symptoms classification criteria patterns syndrome table antibodies antibody autoantibodies hematology nephritis nephrology pericarditis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Manifestations: Malar ... Workup: - ANA ... #Summary #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Anti-phospholipid) M Malar ... Antinuclear Antibody (ANA ... #IMDAMNSHARP #sle ... erythematosus #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Workup: - ANA ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... erythematosus (SLE ... erythematosus (SLE ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
Diagnostic Criteria for Systemic Lupus Erythematosus - ACR and SLICC Criteria #Diagnosis #Rheumatology #SLE #Lupus #Erythematosus #Criteria
Criteria for Systemic Lupus ... Erythematosus - ACR and ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
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 Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... involvement 3% SLE-Related ... Auto-Antibodies: - ANA ... Lupusreference #SLE ... #differential #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... lupus nephritis ... searched for when ANA ... erythematosus #diagnosis #rheumatology ... #table #ANA
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... domain: Pleural or pericardial ... low C4, Low C3 and ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... Non-autoimmune rheumatologic ... Serositis: • Pleural/pericardial ... Photosensitivity • Malar
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