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diagnosis erythematosus systemic differential antinuclear treatment antibodies antibody classification cytoplasmic druginduced summary testing activation autoantibodies cerebritis cns comparison criteria dil
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... erythematosus (SLE ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Manifestations: Malar ... Workup: - ANA ... #Summary #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... Patterns and Associated ... erythematosus (SLE ... (SLE), Systemic ... #patterns #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
: - SLE, SSc ... : - SjS, SLE, ... anti-Su/Ago • Golgi/polar ... ARUPConsult @ARUPLabs #ANA ... differential #diagnosis #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Anti-phospholipid) M Malar ... Antinuclear Antibody (ANA ... #IMDAMNSHARP #sle ... erythematosus #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Workup: - ANA ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... involvement 3% SLE-Related ... Auto-Antibodies: - ANA ... Lupusreference #SLE ... #differential #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... domain: Pleural or pericardial ... low C4, Low C3 and ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... Non-autoimmune rheumatologic ... Serositis: • Pleural/pericardial ... Photosensitivity • Malar
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