157 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... Liver #Enzymes #LFTs ... #Cholestatic #Transaminitis
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminases / Transaminitis ... Metabolic: Wilson Disease ... images/10587 #Transaminitis ... Differential #Diagnosis #causes
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... hepatology #algorithm #Transaminitis ... #LFTs #hepatitis
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Pneumonitis • Treatment ... Connective Tissue Disease ... BrighamChiefs #ILD #Causes ... interstitial #lung #disease
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... • Asplenia Laboratory ... End-stage renal disease ... HbA1c #HgbA1c #Laboratory
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... GI. uterine) Laboratory ... factor VIII) Treatment ... VonWillebrand #Disease
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... PT, aPTT(liver disease ... gastric bypass), LFT ... (liver disease) ... patients if the cause
Unintentional Weight Loss in Primary Care
 • Definition: More than 5% reduction in body weight within
evaluation: CBC, BMP, LFTs ... UA Most Common Causes ... gastrointestinal disease ... - Rheumatic disease ... (7%) - Renal disease
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Cholestatic disease ... • Others #LFTs ... Diagnosis #Algorithm #Causes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... of cholestatic disease ... Alcoholic liver disease ... differential #Hepatology #transaminitis ... #LFTs #RValue #