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diagnosis hepatology differential tests chemistry function hepatitis hepatocellular interpretation lactate acidosis aih algorithm alkphos astalt autoimmune bilirubin causes cholestatic classification
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... • AST/ALT elevation ... #Enzymes #LFTs ... #Cholestatic #Transaminitis
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... Hepatocellular injury ... 2: Cholestatic injury ... #FunctionTest #LFTs ... #Elevation #Transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... injury) • Ischemic ... Function #Tests #LFTs ... Diagnosis #hepatology #transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Bilirubin - +/- elevation ... Enzyme Elevation ... differential #Hepatology #transaminitis ... #LFTs #RValue #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... hepatology #algorithm #Transaminitis ... #LFTs #hepatitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... (LFTs) - Normal ... hepatocellular injury ... Function #Tests #LFTs ... #Laboratory #Values
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... In liver, 80% of ... hepatocyte - Elevation ... Chemistry #Tests #Laboratory ... Pathophysiology #Diagnosis #LFTs
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... hepatocellular pattern of liver ... injury, though ... (rare) - IgG Elevation ... Necrosis) If mild laboratory
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate Elevation ... or renal injury ... / hypoxemia -> focus ... - assess other laboratory ... Injury: • Reduced
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