35 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... environmental triggers ... yrs old; F>M Signs ... /Symptoms: - Fever ... #Pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... Osteoporosis #Systemic ... Complications #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... SLE) - Typical Signs ... /Symptoms Alopecia ... #Symptoms #diagnosis ... #rheumatology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
artery tenderness, triggered ... pupil (AACG) • Systemic ... symptoms and signs ... ) • Temporal arteritis ... Diagnosis #Algorithm #neurology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... (RA) or systemic ... / Symptoms: - ... Sjogrens #Syndrome #Pathophysiology ... #Symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... , holster sign, ... myositis, and arthritis ... Myositis #diagnosis #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
, neurologic, and ... sx + signs/sx of ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... into serum • Triggers ... TLS #diagnosis #management ... #hematology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
susceptibility, infectious triggers ... episode (30%) Systemic ... low ferritin, arthritis ... Disease #AOSD #rheumatology ... #diagnosis #management