68 results
rheumatology syndrome neurology hepatology oncology dermatology disease algorithm hemeonc hemophagocytic lymphohistiocytosis classification gastroenterology lupus signs anemia aosd aplastic arteritis causes
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Common Signs and Symptoms ... Pathophysiology ... Treatment Approach ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
symptoms can mimic ... Diagnosis via genetic ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... into serum • Triggers ... Syndrome #TLS #diagnosis ... #management #hematology
Thyrotoxic Periodic Paralysis - Illness Script • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
any etiology • Trigger ... and menses • Pathophysiology ... thyroid hormone • Symptoms ... or high T3 • Treatment ... Periodic #Paralysis #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... Auto-amplification loop Diagnosis ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... varies depending on trigger ... autoimmune disease, treatment ... #Treatment #management ... #hematology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
environmental triggers ... HLA-DR4 mutation ... old; F>M Signs/Symptoms ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Tetralogy of Fallot Summary • Anatomy • Incidence • Pathophysiology • Presentation • Common Variants •
• Incidence • Pathophysiology ... palliation • Post-Op Management ... Tetralogy #Fallot #diagnosis ... #management #cardiology ... peds #pediatrics #treatment
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Polycythemia Vera (PV) - Diagnosis ... and Management ... Summary Diagnostic ... #Management #Summary ... #treatment #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
the study) • Triggers ... : ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... #management #hematology
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