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differential management causes workup anemia bleeding dermatology erythematosus lupus macrocytic oncology pancytopenia sle thrombocytopenia abnormal activation aptt arteritis autoimmune bruising
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Infection (eg ... CD163 staining of bone ... is found in the bone ... #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... Algorithm Infectious ... Inflammatory • Systemic ... #Algorithm #Causes ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential Diagnosis ... Algorithm Consumption ... HLH syndrome 5. ... marrow failure syndrome ... #Algorithm #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Algorithm Decreased ... Non-lmmune: • HELLP Syndrome ... #Algorithm #Causes ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential Diagnosis ... Algorithm Consumption ... HLH syndrome 5 ... marrow failure syndrome ... #Algorithm #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
- Differential Diagnosis ... Algorithm Thrombocytopenia ... Rare • Drugs (e.g ... #Algorithm #Causes ... #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... antiinflammatory properties e.g ... #Rheumatology # ... diagnosis #management ... #Dermatology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Low in bone marrow ... of substrate (e.g ... #Diagnosis #Workup ... #Hematology #Microcytic
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... permeability Diagnosis ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
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