305 results
signs management differential syndrome treatment neurology causes hematology msk rheumatology psychiatry algorithm comparison complications hepatology dermatology oncology pulmonary cardiology ophthalmology
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease ... Pathophsiology ... in GBA1 gene Clinical ... Osteonecrosis, bone ... #Symptoms
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... - Highest • Bone ... Most common symptoms ... - Bone symptoms ... #Differential #Diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... extrapulmonary cases Clinical ... decreased reflexes Pathophysiology ... of bacilli to bone ... CMC_IM #Potts #Disease
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
treatment of renal bone ... disease and cinacalcet ... which reduces bone ... #Pharmacology #Pathophysiology
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 Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Pathogenesis and clinical ... mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis ... Secondary #Tertiary #pathophysiology
Rheumatoid arthritis (RA): X-ray features • Soft tissue swelling (best seen by comparing left & right
Narrowing • Bony ... the articular bone ... #RA #HandXray #Diagnosis ... #Radiology #Clinical ... #Pathophysiology
Osteoarthritis (OA): Clinical findings • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Osteoarthritis (OA): Clinical ... in subchondral bone ... Osteoarthritis #OA #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma Diagnosis ... Management Summary Clinical ... demineralization) • Renal disease ... pathologic fx) Diagnosis ... Multiple #Myeloma #Diagnosis
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