38 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Hypophosphatasia Is Low Alkaline ... neuropathy • Renal ... : - Renal failure ... Hyophosphatasia #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... growth) Alkaline ... - Highest • Bone ... Pregnancy - Renal ... Diagnosis #Algorithm #hepatology
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Tumours - See Bone ... Pelvis - Positive Alkaline ... Phosphatase Renal ... Secondary to Chronic Renal ... Gastrointestinal Disease • Bone
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
abnormality vs bone ... Transaminase >> Alkaline ... Cholestatic Pattern - Alkaline ... Transaminitis #diagnosis #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
, lungs, RBCs Alkaline ... AlkP) - Liver, bone ... brain, NOT in bone ... pancreas, NOT in bone ... Interpretation #diagnosis #hepatology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
D) Increased bone ... Multiple myeloma (bone ... breast, lung, renal ... lung cancer • Renal ... Dietary • Milk-alkali
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Tests - AST, ALT, Alkaline ... within liver Alkaline ... Other locations: bone ... AlkPhos #Bilirubin #Hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Boxes in yellow ... Green boxes indicate ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... Abnormal #Algorithm #Hepatology
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Renal Failure, Post-Renal ... Cytokine-Mediated Bone ... Lymphomas) Metastatic Bone ... Milk Alkali) •
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
due to increased bone ... Pseudohyperparathyroidism, Renal ... Milk (calcium)-alkali