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diagnosis symptoms msk complications orthopedics carpal disease management pediatrics radiology syndrome wrist endocrinology fracture osteoporosis pagetsdisease peds psychiatry xray agammaglobulinemia
Age of Ossification of Carpal Bones Capitate - 1 Month Hamate - 2 Months Triquetral - 3 Years Lunate -
Age of Ossification ... of Carpal Bones ... Hamate - 2 Months Triquetral ... of the carpal bones ... #Age #Carpal #Bones
Ossification of Carpal Bones It’s always tricky to remember the age of ossification of the carpal bones
Ossification of ... remember the age of ossification ... and sequence of ossification ... -6-7 years for Triquetral ... drdevradiology #Ossification
Triquetral Fracture The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
The triquetrum ... fractured carpal bone ... "pooping duck sign ... common carpal bone ... "pooping duck sign
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... chondrocytes -> Incr ossification ... activates lipolysis Signs ... endocrinology #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... , Fragile bones/ ... easily/weakness, Bone ... Secondary #Tertiary #pathophysiology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease Pathophsiology ... Osteonecrosis, bone ... Disease #Diagnosis #Signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Complications #pathophysiology ... #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... onto lateral hip Signs ... msk #diagnosis #pathophysiology ... #signs #symptoms
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