43 results
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... storage disorder • Deficiency ... #Gauchers #Disease ... Diagnosis #Signs #Symptoms
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
Suspected Celiac Disease ... • Signs and symptoms ... of celiac disease ... • Iron-deficiency ... Diagnosis #Algorithm #gastroenterology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Malnutrition • Wilson's disease ... • Vitamin C deficiency ... Pernicious anemia/B12 deficiency ... collection with EDTA Pathophysiology ... mineralization Symptoms
Functional Dyspepsia - Signs, Symptoms and Pathophysiology
Delayed gastric emptying - Postprandial fullness, nausea, vomiting
Hypersensitivity to gastric
Dyspepsia - Signs, Symptoms ... and Pathophysiology ... nonerosive reflux disease ... #gastroenterology ... #symptoms #diagnosis
Magnesium Deficiency and Alcoholism

Risks associated with Mg deficiency in alcoholism:
 • Affects protein synthesis. energy production,
Magnesium Deficiency ... atherosclerotic CVS disease ... • Depressive symptoms ... • Mg deficiency ... Alcoholism #alcohol #pathophysiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... improvement in symptoms ... composite endpoint of all-cause ... alissa_shega #iron #deficiency
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... decreased reflexes Pathophysiology ... should be done in ALL ... Residency @CMC_IM #Potts ... #Disease #Tuberculosis
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... Inflammatory bowel disease ... Chronic diarrhoea, Short ... drkeithsiau #Copper #Deficiency ... #riskfactors #symptoms
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... : • GH deficiency ... : - Short ... endocrinology #pathophysiology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
with vitamin A deficiency ... conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... diagnosis #signs #symptoms