46 results
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
- Differential Diagnosis ... Algorithm Elevated ... Miscellaneous - Bone ... #Algorithm #causes ... #endocrinology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... • XR, MRI to ... BrighamChiefs #Bone ... #differential #diagnosis
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
Bone Lesion on X-Ray ... /or Non-Active Bone ... • Unicameral Bone ... • Aneurysmal Bone ... #Causes
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Primary Bone Tumors ... - Differential Diagnosis ... • Aneurysmal Bone ... Histiocytoma #Primary #Bone ... #Causes #Oncology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... hyperplasia of bone ... Hemolytic #Anemia #Algorithm ... #Differential #Causes
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... - Accelerated Bone ... Formation: Hungy Bone ... #Management #endocrinology ... #differential #algorithm
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
D) Increased bone ... Paget's disease of bone ... Multiple myeloma (bone ... #endocrinology ... #diagnosis #differential
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... swelling of the bone ... • Bone and joint ... Rule out other causes ... - MRI: inflammation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Algorithm ALP ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... Renal disease - Bone
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... due to increased bone ... Hypercalcemia #Causes ... #differential #diagnosis ... calcium #high #endocrinology