63 results
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... - Highest • Bone ... Most common symptoms ... - Bone symptoms ... Differential #Diagnosis #Algorithm
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Differential Diagnosis Algorithm ... Tumours - See Bone ... • Bone Marrow ... Differential #Diagnosis #Algorithm ... #Orthopedics #Causes
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Differential Diagnosis Algorithm ... Peripheral Vascular Disease ... fractured long bone ... Marfan's Syndrome ... #Orthopedics #Causes
Alpha-gal Syndrome (AGS) - Diagnosis Algorithm
Does patient have recurrent episodes of urticaria, angioedema or isolated GI
Alpha-gal Syndrome ... AGS) - Diagnosis Algorithm ... affirms ≥2 of these boxes ... - Nighttime symptoms ... often an early symptom
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
(IBS) - Pathophysiology ... and Management Algorithm ... factors affecting symptom ... #Pathophysiology ... Diagnosis #Management #Algorithm
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
, Kidney Disease ... - Accelerated Bone ... Formation: Hungy Bone ... Syndrome - ... #differential #algorithm
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Gauchers #Disease ... Diagnosis #Signs #Symptoms
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... HLH syndrome 5. ... marrow failure syndrome ... Metastatic Disease ... Differential #Diagnosis #Algorithm