15 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Pseudotumor - Infectious ... • CMV • HIV ... • Acne • Allergy ... History of Bleeding, Infection ... Algorithm #Causes #Hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and M panel Management ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • Infectious ... Coxsackie, CMV, EBV, HIV ... Disease #diagnosis #management ... #treatment #rheumatology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Framework The DDx ... NSAIDs/Aspirin, IV ... • Parasitic infections ... #Diagnosis #hematology ... #allergy
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... and thymoma DDX ... Anemia #oncology #hematology ... #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... skin necrosis (at injection ... Management: • ... re-challenge >100d after Dx ... #Treatment #Hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... polymicrobial infection ... in case of PCN allergy ... Lung Abscess Differential ... Abscess #pulmonary #differential
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Diagnosis and Management ... Secondary Causes: - Allergic ... hypersensitivity - Infection ... eosinophilia #diagnosis #hematology ... #differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
initiation • Differential ... Diagnosis: Infection ... • Steroids: IV ... APML #diagnosis #management ... #hematology #oncology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Allergic reaction ... Infection - Infection ... Extremely rare - HIV ... Transfusion #diagnosis #management ... #hematology #reactions