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diagnosis hematology pathophysiology signs management msk clinical oncology radiology carpal pediatrics wrist anemia aplastic bronchoscopy chronic cll lymphocytic mri orthopedics
Age of Ossification of Carpal Bones Capitate - 1 Month Hamate - 2 Months Triquetral - 3 Years Lunate -
Age of Ossification ... of Carpal Bones ... Hamate - 2 Months Triquetral ... of the carpal bones ... #Age #Carpal #Bones
Ossification of Carpal Bones It’s always tricky to remember the age of ossification of the carpal bones
Ossification of ... remember the age of ossification ... and sequence of ossification ... -6-7 years for Triquetral ... drdevradiology #Ossification
Triquetral Fracture The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
Triquetral Fracture ... The triquetrum ... fractured carpal bone ... common carpal bone ... fracture • Complications
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... Transformation: • Complication
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... with no early symptoms ... kinase (BTK) Complications ... Warm AIHA • Bone ... • GI complications
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Script Signs and symptoms ... with hypocellular bone ... neutropenic fever) Complications ... to MDS or acute leukemia
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... (MM, Lymphoma, Leukemia ... pathophysiology #signs #symptoms
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... chondrocytes -> Incr ossification ... lipolysis Signs/Symptoms
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... Splenomegaly 5) Symptoms ... thrombocytopenia Complications ... Constitutional symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms
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