72 results
Hyperphosphatemia - Differential Diagnosis Algorithm
Transcellular Shift:
 • Rhabdomyolysis
 • Tumor Lysis
 • Metabolic or Respiratory Acidosis
Rhabdomyolysis • Tumor ... Lysis • Metabolic ... Hyperlipidemia • Tumor ... Lysis #Hyperphosphatemia ... Diagnosis #Algorithm #endocrinology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ICU transfer • Tumor ... lysis kbs every ... MatthewHoMD #TLS #Tumor ... diagnosis #management #oncology
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... Pathophysiology: → Massive tumor ... cell lysis → Release
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology of Tumor ... Lysis Syndrome ... (TLS) Tumor Cell ... Lysis -> Release
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
nephropathy • Solid tumors ... Interleukin-2) • Tumor ... lysis syndrome ... #AKI #Cancer #Oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... of tumor cells ... rate or large tumor ... #Leukostasis #Tumor
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... wandering_er #Tumor ... #Lysis #Syndrome ... #TLS #oncology
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... worsens above #Tumor ... #Lysis #Syndrome ... Pathophysiology #oncology
Gastric Neuroendocrine Tumor (NET) Types
Type 1 - Chronic atrophic gastritis and pernicious anaemia
Type 2 - Zollinger
Neuroendocrine Tumor ... Neuroendocrine #Tumor ... Classification #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... HEMATOLOGIC ONCOLOGIC ... STRUCTURAL ONCOLOGIC ... EMERGENCIES: Tumor ... Lysis Syndrome: