105 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... TumorLysis #syndrome #TLS ... #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... TumorLysis #Syndrome #TLS ... #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... : Lysis of tumor ... rate or large tumor ... #Leukostasis #Tumor
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome (TLS ... Abnormalities of TLS ... Laboratory TLS ... #diagnosis #management
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ICU transfer • Tumor ... MatthewHoMD #TLS ... #Tumor #Lysis # ... Syndrome #diagnosis
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Causes of Peripheral Weakness with Sensory Changes - Differential Diagnosis Algorithm
Radiculopathy:
 • Disc
 • Spondylosis
 •
- Differential Diagnosis ... Spondylosis • Tumor ... • Trauma • Tumor ... • Diabetes • Tumor ... Weakness #Sensory #Neurology
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... worsens above #Tumor ... Lysis #Syndrome #TLS ... #Pathophysiology
Causes of Facial Weakness - Differential Diagnosis Algorithm
Forehead Sparing = Central cause
  - Most commonly
- Differential Diagnosis ... - Intracranial tumor ... Infection, Compression Tumor ... #Differential #Diagnosis ... Algorithm #Causes #neurology
Causes of Orthopnea - Differential Diagnosis Framework

 • Fear and Anxiety
 • Pleural Effusion
 • Ascites
- Differential Diagnosis ... - CNS lesion: ALS ... Compressive mediastinal tumors ... #Differential #Diagnosis ... #Causes #pulmonary