33 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... phosphate crystals #TumorLysis ... #syndrome #TLS
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... Hyperkalemia #TumorLysis ... #Syndrome #TLS
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... gluconate #TumorLysis ... #diagnosis #management ... #oncology
Gastric Neuroendocrine Tumor (NET) Types
Type 1 - Chronic atrophic gastritis and pernicious anaemia
Type 2 - Zollinger
Neuroendocrine Tumor ... Zollinger Ellison syndrome ... Neuroendocrine #Tumor ... Classification #oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... ICU transfer • Tumor ... MatthewHoMD #TLS #Tumor ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... : Lysis of tumor ... rate or large tumor ... #Leukostasis #Tumor
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
nephropathy • Solid tumors ... Capillary leak syndrome ... Interleukin-2) • Tumor ... lysis syndrome ... #AKI #Cancer #Oncology
Meigs Syndrome - Diagnosis and Management Summary
Triad:
1) Pleural effusion + 
2) Ascites + 
3) Benign Ovarian
Meigs Syndrome - ... Diagnosis and Management ... Benign Ovarian Tumor ... removal of the tumor ... SCVMCMed #Meigs #Syndrome
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... worsens above #Tumor ... #Lysis #Syndrome ... #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... Hyperviscosity Syndrome ... Superior Vena Cava Syndrome ... EMERGENCIES: Tumor ... Lysis Syndrome: