146 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology of Tumor ... Lysis Syndrome ... (TLS) Tumor Cell ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... (TLS) and Treatment ... Laboratory TLS ... #TumorLysis #Syndrome
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ICU transfer • Tumor ... MatthewHoMD #TLS ... #Tumor #Lysis # ... Syndrome #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... Pathophysiology: Lysis of tumor ... rate or large tumor ... #Leukostasis #Tumor
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Polycystic Ovarian Syndrome ... Hyperthecosis • Tumor ... • Cushing's Syndrome ... Tumor Low Serum ... Diagnosis #Algorithm #endocrinology
Gynecomastia - Differential Diagnosis Algorithm
No Testicular Mass on Ultrasound
 • Adrenal Neoplasm
 • Increased Extraglomerular Aromatase
• Leydig Cell Tumor ... • Sertoli Cell Tumor ... Klinefelter's Syndrome ... • Kallman's Syndrome ... Algorithm #causes #endocrinology
Adrenal Incidentalomas: Hormone Evaluation
 • Zona Glomerulosa: Primary Hyperaldosteronism?
    - Aldosterone and renin
Fasciculata: Cushing Syndrome ... for those with tumor ... mendesthiagob #Adrenal #Tumors ... Diagnosis #workup #endocrinology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
SAME, Cushing Syndrome ... Renin secreting tumor ... diuretics, Bartter syndrome ... , Gitelman syndrom ... potassium #low #nephrology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... #Presentation #TLS