21 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • Transfusion reactions ... #Hemolytic #Anemia ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
1) DIAGNOSE AIHA ... • Anemia: macrocytic ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Other: Transfusion reaction ... Extravascular #Causes ... #hematology #anemia
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... fever • Drug reactions ... #Differential #Diagnosis ... #hematology #rheumatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... Causes of false- ... amyloidosis Other causes ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... without other cause ... #Transfusion #Reactions ... #hematology #diagnosis ... #comparison #table
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... 5) Symptoms of anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential Diagnosis ... Idiosyncratic drug reactions ... Megaloblastic anemia-rare ... #differential #diagnosis ... #causes #hematology