21 results
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
CREST Syndrome: ... tightening of skin ... TELANGIECTASIA (In face, hands ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... inhibitors • Uveitis- Ophthalmology ... #signs #symptoms
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Cushing's Syndrome ... Abdominal Striae, Thin Skin ... the patient's hand ... Next diagnostic ... #Signs #MoonFacies
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Ophthalmologic ... Cardiovascular and ... vital sign abnormalities ... Hyperthermia UCSD ... #diagnosis
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... arthritis (19% ... see mechanics hands
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Reactive Arthritis ... Transient • Skin ... keratotic lesions on hands ... pathophysiology #diagnosis ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
: Pathogenesis and ... like rheumatoid arthritis ... Xeroderma (Dry skin ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
of the joints (arthritis ... Episcleritis Signs ... of the joints (arthritis ... Leukemia cutis Diagnosis ... #diagnosis #dermatology
What is a Boxer’s fracture?? Fracture of the 4th or 5th metacarpal neck
 - Common in
falls onto the hand ... ulnar part of hand ... Always check for skin ... – compartment syndrome ... #Metacarpal #Diagnosis
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
wane; diagnosis ... trauma leads to skin ... painless, no systemic signs ... Infection #clinical #photo ... #hand