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Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... double-stranded DNA ... Anti-centromere, Scl-70 (DNA ... topoisomerase I), RNA
Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess,
Hypovolemia, UNa ... Hypovolemia, UNa ... Trauma Euvolemia, UNa ... Hypervolemia, UNa ... Hypervolemia, UNa
Rifamycins - Antibiotics Class Overview Include Rifampin, Rifaximin, Rifapentine, Rifabutin. Mechanism: Inhibits bacterial DNA-dependent RNA polymerase (unique mechanism).
Inhibits bacterial DNA-dependent ... RNA polymerase
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine Na ... +K / serum Na >1 ... or Ineffective (UNa ... solute intake, UNa
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
investigations depending on clinical ... Vasculits: ANCA, ANA ... Anti-GBM, Anti-ds-DNA ... , C3/C4, ENA, immunoglobulins
Some of the techniques used for Antenatal Diagnosis Amniocentesis - Chromosome/micro-array and DNA analysis -
micro-array and DNA ... micro-array and DNA ... surgery, e.g. laser photo-coagulation ... diagnosis — free fetal DNA
Hyponatremia Diagnosis Algorithm UOsm ≥ POsm - Vasopressin-Dependent • UNa < 20 mEq/L - Appropriate (↓ EABV)
Vasopressin-Dependent • UNa ... Cirrhosis • UNa
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
- RAAS ON (UNa ... - RAAS OFF (UNa
Polychromatophilia - Note 2 large blue-gray erythrocytes as seen on H&E stain. On a stain for
show retained RNA ... The left photo also ... and the right photo ... #Clinical #Path
Osler's Nodes: Painful, erythematous nodules associated with bacterial endocarditis. Photo credit, Josh Fierer, M.D. Charlie Goldberg, M.D.
Photo credit, Josh ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology
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