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management oncology differential syndrome algorithm mds myelodysplastic anemia antinxp2 antinxp2dm aplastic classification coagulation comparison dermatomyositis dic disorders disseminated eosinophil eosinophilia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... effect following treatment ... #Algorithm #Causes ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... by a hemophilia treatment ... Avoid meds that ... #Management #treatment ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... Low calcium • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
+ Bleeding Treatment ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... - Differential Diagnosis ... hypertension and/or drug treatment ... #differential #diagnosis ... #causes #hematology
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