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management differential oncology dermatology disease lupus sle algorithm autoimmune classification erythematosus table vasculitis anemia antibody comparison disorders eosinophils hes hypereosinophilia
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential Diagnosis ... Lymphomas - Systemic ... Hypereosinophilic Syndrome ... #Causes #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... (common causes ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... Secondary Causes ... Hypereosinophilia #Syndrome ... #diagnosis #hematology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... Anti-UI-ribonucleoprotein ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • MCTD: Anti-UI ... • Scleroderma (Systemic ... Autoantibodies #Rheumatology ... #diagnosis #associations
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... guidelines General - Systemic ... cell disease Rheumatology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... • Sjögren syndrome ... ANCA+ 60% • Eosinophilic ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
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