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diagnosis management hematology oncology erythematosus myelodysplastic neurology sle summary systemic activation acute aki anemia aortitis aplastic associations autoantibodies behcets bilateral
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Puncture, EEG Treatment ... Maheswaranathan, MD ... CNS #neurology #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... LAC) • Sjogren Syndrome ... • MCTD: Anti-UI ... Maheswaranathan, MD
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Anti-UI-ribonucleoprotein ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... immunosuppressive meds ... immunosuppressive meds ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... #MDS #Diagnosis ... #Management #treatment ... #hematology #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... (RA), Systemic lupus ... (SPA) • Other Causes ... Maheswaranathan, MD ... Differential #Diagnosis #rheumatology
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
Bilateral B-Lines in case ... Pneumonia on Lung POCUS ... POCUS lung exam ... travel hx, home meds ... Progressive URI
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 Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... muscles: “myasthenic crises ... Myasthenia Crises ... immunosuppressants - Meds
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