25 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management Summary ... old, ~10,000 new cases ... only curative treatment ... #hematology #oncology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Erythematosus - Summary ... block • Sjogren syndrome ... Anti-UI-ribonucleoprotein ... severe disease Treatment ... #diagnosis #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... Positive in 60-80% of cases ... life-threatening • Treatment ... Diagnosis #Management #Summary ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment ... diagnosis #management #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Trials and Evidence Summary ... NEJM 1999 - ICU FOCUS ... unnecessary and cause ... Transfusion #Thresholds #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... SAPHO syndrome is ... Rule out other causes ... and lower jaw Treatment ... #Rheumatology #
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... Classify severity Treatment ... by a hemophilia treatment ... Avoid meds that ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Drugs, Unknown cause ... Treatment: • ... 100 mg/m2) : in case ... diagnosis #management #treatment ... #summary #rheumatology