35 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Salt Wasting vs SIADH ... - Pathophysiology ... → Increased urine ... #Pathophysiology ... #diagnosis #nephrology
Hyponatremia - Diagnostic Evaluation Algorithm

Step 1: Consider whether Posm may actually be normal or elevated
Step 2:
Check Uosm and/or Urine ... status and measure UNa ... tests Step 5: If SIADH ... Hyponatremia #Diagnosis #Workup
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... WBCs, or urine ... → Urine culture ... Diagnosis #Algorithm #Workup ... #urine
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Osmolarity 2) Urine ... Osmolarity 3) Urine ... Low Uric Acid → SIADH ... Diagnosis #Algorithm #nephrology
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Vasopressin-Dependent • UNa ... Cirrhosis • UNa ... Inappropriate - Consider: SIADH ... algorithm #causes #nephrology
Urine Specific Gravity - Interpretation
Specific Gravity = Density of urine / Density of water
SG close to
Urine Specific Gravity ... Gravity = Density of urine ... Dehydration • SIADH ... EricsMedicalLectures/ #Urine ... #differential #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
volume-based algorithm Urine ... restriction alone in SIADH ... or Ineffective (UNa ... Present (Uosm ≥100): SIADH ... table #sodium #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
uric acid >4 • Urine ... Extra-renal losses • Urine ... uric acid <4 • SIADH ... uric acid >4 • Urine ... #sodium #low #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... 0.9% NS • If Urine ... osmolality < 538 AND UNa ... Hypotension, Increased urine ... #hyponatremia #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... differential, urine ... dipstick, urine ... blood culture, urine ... #Injury #AKI #Workup