12 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... →Activation of CD8 ... Auto-amplification loop Diagnosis ... Lymphohistiocytosis #diagnosis ... treatment #summary #rheumatology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... CD13, CD33, CD34, HLA-DR ... , CD3 Chronic ... Blood #Disorders #hematology ... #Differential #Diagnosis
Amebiasis - Balamuthia mandrillaris Life Cycle
1) Cysts
2) Trophozoite
3) Mitosis
4) Amebae (cysts and trophozoites) can enter humans
Amebiasis - Balamuthia ... #Amebiasis #Balamuthia ... mandrillaris #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc
Amebiasis - Naegleria fowleri - Life Cycle
1) Cysts
2) Trophozoite
3) Flagellated Form
4) Promitosis
→ Water-related activities such as
Amebiasis - Naegleria ... occasionally in CSF #Amebiasis ... fowleri #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc
Amebiasis - Acanthamoeba Life Cycle
1) Cysts
2) Trophozoite
3) Mitosis
4) Amebae (cysts and trophozoites) can enter humans in
Amebiasis - Acanthamoeba ... #Amebiasis #Acanthamoeba ... #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Arthritis of the Hand - Arthritis Patterns

Osteoarthritis:
• Osteoarthritis of the hand usually involves the DIP and
subluxation causing ulnar ... PIP + DIP + 1st CMC ... patterns #hand #diagnosis ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
diagnostic consideration ... Pathophysiology ... of NK cells and CD8 ... Diagnostic Criteria ... #Management #Hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... counts may delay diagnosis ... #differential #diagnosis ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... back pain) • HLA-B27 ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology