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rheumatology differential dermatology pathophysiology sle systemic erythematosus syndrome biliary causes cirrhosis hepatology joint pbc workup arthritis arthropathies arthropathy autoantibodies autoimmune
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Hypersensitivity vasculitis ... lesions • Discoid lupus ... #differential #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... , Vasculitis, Purpura ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... the context of primary ... pain • Swan neck/Ulnar ... : • Symptoms limited
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... / Symptoms: - ... Xeroderma (Dry skin ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... Abnormalities in primary ... (lupus, RA, Sjogren's ... cryoglobulins • Skin
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Algorithm Symptoms ... quadrant discomfort Signs ... of autoimmune disease ... #Algorithm #hepatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin ... Malar (butterfly) Rash ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... sclerosis, Still's disease ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... Algorithm Monoarthritis ... arthritis - with the skin ... should have other symptoms ... like “butterfly rash
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