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Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Nephritic #Nephrotic ... Comparison #Algorithm #Nephrology
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
pressure - Normal/low ... Red blood cell casts ... Serum albumin - Low ... Red blood cell casts ... edgarvlermamd - Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... Hypothyroidism, Low ... failure, Cirrhosis, Nephrotic ... diagnosis #sodium #low ... #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... Cirrhosis • Nephrotic ... Hypo-osmolar urine ... Diagnosis #Algorithm #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... Cirrhosis • Nephrotic ... Hypo-osmolar urine ... Diagnosis #Algorithm #Causes
True Hyponatremia Differential Algorithm

Instead (or in addition) of volume status examination, check urine sodium and serum
uric acid: - Urine ... sodium low, uric ... - Urine sodium ... and uric acid low ... Algorithm #Diagnosis #Nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Osmolarity 2) Urine ... Osmolarity 3) Urine ... Uric Acid - Low ... Diagnosis #Algorithm #nephrology
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Hyponatremia - Differential ... Beer Potomania - Low ... liver failure, nephrotic ... Diagnosis #Algorithm #causes ... #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... 145 mmol/L High Urine ... mannitol, glucosuria Low ... Urine Osmolality ... #Nephrology #Differential