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diagnosis differential algorithm causes management clinical dermatology endocrinology hematology pathophysiology emergencies hepatology oncologic skinrash treatment ascites atopic atopy bancrofti blood
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
• Spontaneous bleeding ... • Shortness of breath ... sustained over a one-hour ... • Dyspnea at rest ... Hypercalcemia
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - ... Hypocalciuric Hypercalcemia ... renal, Bladder, Breast ... Miscellaneous - Bone ... Hyperthyroid, Bony
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Hypercalcemia - ... Hypocalciuria Hypercalcemia ... Breast, Kidney, ... Cytokine-Mediated Bone ... Lymphomas) Metastatic Bone
Primary Bone Tumors - Differential Diagnosis Algorithm Metastatic - Most common tumour in adults - Breast
Primary Bone Tumors ... in adults - Breast ... • Aneurysmal Bone ... #Bony #Tumors # ... Orthopedics #Causes #Oncology
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
Hypercalcemia of ... resorption in the bone ... resorption in the bone ... lung, Renal Cell, Breast ... @kdjhaveri #Hypercalcemia
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... D) Increased bone ... Paget's disease of bone ... Multiple myeloma (bone ... metastases: thyroid, breast
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
fever, joint pain, bleeding ... night sweats, bleeding ... • Significant bleeding ... Intracellular Urate ... Leukemia #Hematology #Oncology
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
3: Necrosis of bone ... destroying thin bony ... into contiguous areas ... postauricular crease ... symptoms #diagnosis #otology
BLT with a Kosher Pickle - Mnemonic for Cancers that Metastasize to Bone B - Breast L
Metastasize to Bone ... B - Breast ... #Metastasize #Bone ... Osseous #Mets #Oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Simultaneous clotting and bleeding ... , shortness of breath ... , shortness of breath ... plasmapheresis Hypercalcemia
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