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diagnosis differential hypercalcemia causes endocrinology hematology oncology radiology bonetumors hepatitis hepatology highcalcium injury leukemia liver malignancy malignant msk orthopedics pathophysiology
Primary Bone Tumors - Differential Diagnosis Algorithm Metastatic - Most common tumour in adults - Breast
Primary Bone Tumors ... in adults - Breast ... Non-Malignant • Giant Cell ... • Aneurysmal Bone ... #Bone #Bony #Tumors
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
aka. cancerous cells ... more common than primary ... differently from primary ... metastasis: • Breast ... - these cancer cells
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Differential Diagnosis Algorithm ... or normal): • Primary ... renal, Bladder, Breast ... Miscellaneous - Bone ... Hyperthyroid, Bony
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
production: Small cell ... resorption in the bone ... resorption in the bone ... , Breast Cancer, ... Differential #Diagnosis #algorithm
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
structure-related • Primary ... D) Increased bone ... Paget's disease of bone ... Multiple myeloma (bone ... metastases: thyroid, breast
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... bleeding, infections, bone ... Bone marrow • ... • Headaches, bone ... neutropenia) • Bone
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Differential Diagnosis Algorithm ... Primary Hyperparathyroidism ... Breast, Kidney, ... Cytokine-Mediated Bone ... Lymphomas) Metastatic Bone
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Infiltration: Often breast ... CA, small cell ... hemolysis) • ALP: Bone ... differential #diagnosis #algorithm
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... stimulates our body ... Too many cells in ... EPO-independent (primary ... up EPO levels Primary
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