34 results
Granular & “Muddy Brown” Casts on Urine Microscopy
A. Finely granular cast B. slightly coarser granular cast
“Muddy Brown” Casts ... of mb granular casts ... appreciated at low ... Granular #MuddyBrown #Casts ... #Clinical #Nephrology
Polyuria - Differential Diagnosis Algorithm
Polyuria = >3L Urine output / 24 hours
Urine osmolality = 2 (Na
Diagnosis Algorithm ... Polyuria = >3L ... nutrition), Azotemia LOW ... Differential #Diagnosis #Algorithm ... #nephrology
Causes of Polyuria - Differential Diagnosis Algorithm
Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min)
Osmotic
Causes of Polyuria ... Polyuria - Urine ... • Increased urea ... #Nephrology #Differential ... #Causes
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
Polyuria - Differential ... Diagnosis Algorithm ... solute load #Polyuria ... Differential #Diagnosis #Algorithm ... #causes #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... proteinuria, RBC casts ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... diuresis (see Polyuria ... mannitol, glucosuria Low ... Hypernatremia #Nephrology ... #Causes
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
Causes of Polyuria ... • Central Dl (Low ... Mimics (↑ urine ... frequency without ↑ urine ... #nephrology
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... • UA: sterile pyuria ... , WBC casts, eosinophiluria ... proteinuria, granular casts ... #nephrology #diagnosis
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
require urgent nephrology ... : Hypovolemia, Low ... PROBLEM ~80% of AKI cases ... for WBCs, RBCs, casts ... workup #diagnosis #nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
ADH promotes Urea ... Osmolarity 2) Urine ... Uric Acid - Low ... #nephrology #sodium ... #low #uricacid