12 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... (TLS) Tumor Cell ... / Xanthine -> Uric ... Precipitation => • Urate ... #TLS #Pathophysiology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... : • Uric acid ... 8.0 mg/dL • Potassium ... #TumorLysis #Syndrome ... #management #oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... ≥ 8 mg/dL • Potassium ... Treatment of Clinical TLS ... MatthewHoMD #TLS
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : • Pathophysiology ... phos, Elevated uric ... #TLS #diagnosis ... #management #hematology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Urine Na/K/Cl/urea ... PVR - CPK, uric ... acid (rhabdo/TLS ... AcuteKidneyInjury #AKI #Nephrology ... #Diagnosis #Algorithm
Pruritus Treatment Algorithm for Hemodialysis Patients 

Non-PharmacoIogicaI Measures 
 • Use gentle soap e.g. Dove
Pruritus Treatment Algorithm ... except if other areas ... #Hemodialysis #Uremic ... #Uremia #Management ... #Nephrology #CKD
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... HIV, Influenza, TSS ... Dermatomyositis) AKI - Pathophysiology ... Monitor potassium
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... electrolytes, urea ... , uric acid, osmolarity ... • Cardio-renal syndrome ... Differential #Diagnosis #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... HUS = hemolytic-uremic ... syndrome; aHUS ... of the retina, uveae ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... HIV, Influenza, TSS ... Monitor potassium ... Differential #Diagnosis #Management ... causes #treatment #nephrology