71 results
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Extra-renal Losses ... loss (Diarrhea) Renal ... #causes #potassium ... #low #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... • Increased renal ... hypertrophy • Sodium ... #Mechanisms #pathophysiology ... #nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Differential Diagnosis Algorithm ... ADH promotes Urea ... Osmolarity 3) Urine Sodium ... High Uric Acid → renal ... #nephrology #sodium
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic algorithm ... Decreased renal ... • Acute renal ... Hyperkalemia #Diagnosis #algorithm ... #nephrology #potassium
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
minutes) Decrease potassium ... Fluids Shift potassium ... 90 minutes) • Sodium ... (if preserved renal ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
• Refeeding syndrome ... Medications Renal ... Losses Non-renal ... #nephrology #low ... #potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... gastrointestinal K loss • Renal ... hypokalemia • Renal ... #causes #nephrology ... #potassium
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... Defects Fanconi Syndrome ... tubule Bartter Syndrome ... Nephron #Defects #Pathophysiology ... #Nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Na <20: Extra-renal ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... mOsm/kg - Implies renal ... , Ingestion Renal ... , Cushing syndrome ... #nephrology #sodium