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diagnosis differential causes hyperkalemia management tumor acutekidneyinjury hematology hyponatremia hypotonic intercellularshift leukostasis oncology physiologic potassium sodium treatment tumorlysis
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... large amounts of K+ ... ALL, AML, NHL → AKI ... #TLS #Pathophysiology
Tumor Lysis Syndrome (TLS) Pathophysiology Culprits: ALL, Burkitt, SCLC Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... = ↑Phos, ↓Ca, ↑K, ... tetany ↑UA = AKI ... #Syndrome #TLS
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: • Pathophysiology ... fever - ACS, AKI ... Syndrome: • Pathophysiology ... values: Elevated K, ... #Syndrome #TLS
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
- Urine Na/K/ ... Cl/urea/protein/ ... uric acid (rhabdo/TLS ... #Nephrology #Diagnosis ... #Algorithm #Causes
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Acidosis, Cell Lysis ... (TLS, rhabdo/crush ... , RTA Type IV, AI ... Elimination (see Table ... Treatment #potassium #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Differential Diagnosis Algorithm ... Osmoles, Increased Urate ... Tumor Lysis Syndrome ... Decreased Na+-K+ ... IntercellularShift #Nephrology
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