16 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Renal Tubular Defects ... loop of Henle Gitelman ... Localization #Nephron #Defects ... #Pathophysiology ... #Nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Gitelman ... syndrome - ... Genetic defects ... Differential #Diagnosis #Low ... #Magnesium #Table
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... Epithelial #Inherited #Defects ... #Kidney #Nephrology ... #Differential #Table
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
Effects of Strokes ... Artery #Strokes #Syndromes ... #Localization #Effects ... #Neurology #Diagnosis ... #Table #Territories
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Hypercalcemia-PTH effect ... nephrocalcinosis (FHHNC) • Gitelman's ... syndrome • Thiazide ... ab • Genetics defects ... Hypomagnesemia #Magnesium #Low
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... with coagulation defects ... Elevated Liver tests, Low ... Severe coagulation defects ... hematology #diagnosis #table
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... on the Kidney - Pathophysiology ... decreased renal blood flow ... KidneyDisease #nephrology ... #Effects #pathophysiology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Low-normal EABV ... , Low Plasma HCO3 ... Non-reabsorbable anion effect ... , Gitelman syndrome ... algorithm #diagnosis #nephrology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... with coagulation defects ... Elevated Liver tests, Low ... Severe coagulation defects ... Diagnosis #Comparison #Table
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... alkalosis • Normal or low ... #nephrology #management ... #pathophysiology