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diagnosis aki differential microscopy injury kidney kidneyinjury ain atlas blood classification hematuria interpretation key nephritis simplified urinary urology
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
to Acute Interstitial ... sterile pyuria, WBC casts ... hematuria, mild tubular ... proteinuria, granular casts ... Algorithm #nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... tubular necrosis ... suggestive of nephrotic ... suggestive of interstitial ... #nephrology #interpretation
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
cells - Acute tubular ... • White cell casts ... ” - Necrotic tubular ... key #diagnosis #nephrology ... #casts
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Epithelial cell casts ... Obstruction • Cast ... Interstitial Nephritis ... #KidneyInjury #Nephrology
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... are seen in acute ... 34t5DgJ #Urinary #Casts
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... and Diagnosis Algorithm ... repeat testing • Acute ... proteinuria, RBC casts ... #Workup #urology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... renal biopsy • Interstitial ... nephritis: eosinophilia ... #Diagnosis #nephrology
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Urinary obstruction, Nephrotoxic ... PROBLEM ~80% of AKI cases ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts ... KidneyInjury #simplified #workup
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
tubular necrosis ... (causes: sepsis ... , meds, contrast ... interstitial nephritis ... Classification #diagnosis #nephrology
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