20 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... diabetes)) #Glomerular ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... sediment - WBC/RBC casts ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... • Evidence of glomerular ... bleeding (proteinuria ... , RBC casts, dysmorphic ... if cause not identified
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
• White cell casts ... infection • Hyaline casts ... disease • Granular casts ... key #diagnosis #nephrology ... #casts
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... hematuria: - RBC casts ... - Proteinuria ... #urology #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... in a variety of acute ... #Urine #Microscopy ... #nephrology #interpretation
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
arbitrarily defined as urine ... cell/white cell casts ... because nephritic urine ... Nephrocalcinosis causes ... #syndrome #nephrology
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
INTRINSIC: - Glomerular ... red blood cells/proteinuria ... white blood cell casts ... renal tubular cell casts ... or pigmented casts
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach to Acute ... sterile pyuria, WBC casts ... , mild tubular proteinuria ... , granular casts ... AIN #Algorithm #nephrology