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differential causes rheumatology acute aki algorithm diseases injury kidney pulmonary vasculitis antibodies classification glomerulonephritis renal table ana antibody antigbm antineutrophil
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... Disease-specific testing: anti-ANCA ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... #nephrology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... -RNP ANCA-Associated ... Vasculitis: • Microscopic ... + 90% • Anti-GBM ... Antineutrophil #antibodies #diagnosis
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
- Differential Diagnosis ... : Microscopic Polyangiitis ... Churg Strauss) Anti-GBM ... #differential #diagnosis ... #nephrology #causes
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... polyangiitis (GPA), microscopic ... involvement - PR3>MPO Microscopic ... 90%, rarely PR3 Anti-GBM ... #Diagnosis #Rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Graves' disease c-ANCA ... granulomatosis p-ANCA ... Microscopic polyangiitis ... Celiac disease Anti-GBM ... Associations #diseases #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
cytoplasmic antibody (ANCA ... ) + • c-ANCA: ... staining • p-ANCA ... #Differential #Diagnosis ... #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... dipstick, urine microscopy ... Glomerulonephritis / Vasculits: ANCA ... , ANA, Anti-GBM, ... #nephrology #causes
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... glomerular #diseases #nephrology ... comparison #table #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
- Differential Diagnosis ... • Glomerular: ANCA ... Immune-complex disease, Anti-GBM ... #Differential #Diagnosis ... #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
- Differential Diagnosis ... Vasculitis • GN: ANCA ... , Anti-GBM, C3/C4 ... #Differential #Diagnosis ... #nephrology #causes
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